Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo

Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo

Cannabis exposure during gestation evokes significant molecular modifications to neurodevelopmental programs leading to neurophysiological and behavioral abnormalities in humans. The main neuronal receptor for Δ9-tetrahydrocannabinol (THC) is the type-1 cannabinoid receptor CB1R, one of the most abu...

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Bibliographic Details
Main Authors: Rodrigo Del Rio, Rosa G. Serrano, Eric Gomez, Joshua C. Martinez, Marina A. Edward, Rommel A. Santos, Kenneth S. Diaz, Susana Cohen-Cory
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Xenopus laevis
live imaging
optic tectum
knockdown
anandamide (AEA)
2-Arachidonoylglycerol (2-AG)
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2023.1176864/full

Internet

https://www.frontiersin.org/articles/10.3389/fnsyn.2023.1176864/full

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