Polymorphisms in the SLC12A3 Gene Encoding Sodium-Chloride Cotransporter are Associated with Hypertension: A Family-Based Study in the Mongolian Population

Polymorphisms in the SLC12A3 Gene Encoding Sodium-Chloride Cotransporter are Associated with Hypertension: A Family-Based Study in the Mongolian Population

Background/Aims: Hypertension or persistent high blood pressure (BP) is a leading cause of death worldwide. Extensive evidence indicates that the thiazide-sensitive Na+-Cl- cotrans-porter (NCC) affects BP via regulation of renal sodium reabsorption. However, the relationship between genetic variants...

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Bibliographic Details
Main Authors: Caiyan An, Junqing Liang, Kejin Zhang, Xiulan Su
Format: Article
Language:English
Published: Karger Publishers 2016-01-01
Series:Kidney & Blood Pressure Research
Subjects:
Hypertension
Family-based association test (FBAT)
SLC12A3
Mongolian
Haplotype
Online Access:http://www.karger.com/Article/FullText/368543

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http://www.karger.com/Article/FullText/368543

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