Targeting Cellular Metabolism With CPI-613 Sensitizes Pancreatic Cancer Cells to Radiation Therapy

Targeting Cellular Metabolism With CPI-613 Sensitizes Pancreatic Cancer Cells to Radiation Therapy

Purpose: Local tumor progression is a cause of significant morbidity and mortality in patients with pancreatic ductal adenocarcinoma (PDAC) with surgically unresectable disease. Novel and effective approaches to accomplish durable local control are urgently needed. We tested whether CPI-613 (devimis...

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Bibliographic Details
Main Authors: Husain Yar Khan, PhD, Mandana Kamgar, MD, Amro Aboukameel, MS, Sahar Bannoura, MS, Brian Y. Chung, PhD, Yiwei Li, MD, Mohammed Najeeb Al Hallak, MD, Philip A. Philip, MD, PhD, Susan Tsai, MD, Sanjeev Luther, MBA, William A. Hall, MD, Asfar S. Azmi, PhD
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109422002287

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http://www.sciencedirect.com/science/article/pii/S2452109422002287

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