Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges—The Hamburg perspective

Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges—The Hamburg perspective

Models based on human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are proposed in almost any field of physiology and pharmacology. The development of human induced pluripotent stem cell-derived cardiomyocytes is expected to become a step forward to increase the translational powe...

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Bibliographic Details
Main Authors: Djemail Ismaili, Carl Schulz, András Horváth, Jussi T. Koivumäki, Delphine Mika, Arne Hansen, Thomas Eschenhagen, Torsten Christ
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Physiology
Subjects:
hiPSC-CM
hESC-CM
human cardiomyocytes
ion currents
action potentials
computer modelling and simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1132165/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1132165/full

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