A Soft Sensor for Bioprocess Control Based on Sequential Filtering of Metabolic Heat Signals

Soft sensors are the combination of robust on-line sensor signals with mathematical models for deriving additional process information. Here, we apply this principle to a microbial recombinant protein production process in a bioreactor by exploiting bio-calorimetric methodology. Temperature sensor s...

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Bibliographic Details
Main Authors: Dan Paulsson, Robert Gustavsson, Carl-Fredrik Mandenius
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/14/10/17864