A Soft Sensor for Bioprocess Control Based on Sequential Filtering of Metabolic Heat Signals
Soft sensors are the combination of robust on-line sensor signals with mathematical models for deriving additional process information. Here, we apply this principle to a microbial recombinant protein production process in a bioreactor by exploiting bio-calorimetric methodology. Temperature sensor s...
Main Authors: | Dan Paulsson, Robert Gustavsson, Carl-Fredrik Mandenius |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-09-01
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Series: | Sensors |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8220/14/10/17864 |
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