3195 Genomic Analysis of Primary Plasma Cell Leukemia reveals Complex Cytogenetic Alterations and High Risk Mutational Patterns

3195 Genomic Analysis of Primary Plasma Cell Leukemia reveals Complex Cytogenetic Alterations and High Risk Mutational Patterns

OBJECTIVES/SPECIFIC AIMS: 1) Determine the mutational landscape, including translocation, mutations and mutational signatures as well as copy number variations of pPCL and identify significant differences to non pPCL MM. 2) Determine whether genetic changes pertinent to pPCL could be explored as the...

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Bibliographic Details
Main Authors: Carolina Schinke, Eileen Boyle, Cody Ashby, Yan Wang, Davies Christopher Wardell, Sharmilan Thanendrarajan, maurizio Zangari, Frits van Rhee, Gareth Morgan, Brian Walker
Format: Article
Language:English
Published: Cambridge University Press 2019-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866119000311/type/journal_article

Internet

https://www.cambridge.org/core/product/identifier/S2059866119000311/type/journal_article

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