Synthesized Anti-HER2 Trastuzumab-MCC-DM1 Conjugate: An Evaluation of Efficacy and Cytotoxicity

Background: Trastuzumab is a humanized monoclonal antibody that targets site-specifically human epidermal growth factor-2 receptor (HER2) cell surface antigen overexpressed in approximately 20% of human breast carcinomas. Despite its positive therapeutic outcomes, a large proportion of individuals a...

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Bibliographic Details
Main Authors: Soodabeh Shafiee, Roya Mirzaei, Malihe Salehi, Neda Jalili, Amir Taheri, Leila Farahmand
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-09-01
Series:Iranian Journal of Immunology
Subjects:
Online Access:https://iji.sums.ac.ir/article_49411_07f4888549d6cfb0b706534f398c5e5b.pdf