Synthesized Anti-HER2 Trastuzumab-MCC-DM1 Conjugate: An Evaluation of Efficacy and Cytotoxicity
Background: Trastuzumab is a humanized monoclonal antibody that targets site-specifically human epidermal growth factor-2 receptor (HER2) cell surface antigen overexpressed in approximately 20% of human breast carcinomas. Despite its positive therapeutic outcomes, a large proportion of individuals a...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Shiraz University of Medical Sciences
2023-09-01
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Series: | Iranian Journal of Immunology |
Subjects: | |
Online Access: | https://iji.sums.ac.ir/article_49411_07f4888549d6cfb0b706534f398c5e5b.pdf |