SARS-CoV-2 infection causes prolonged cardiomyocyte swelling and inhibition of HIF1α translocation in an animal model COVID-19

SARS-CoV-2 infection causes prolonged cardiomyocyte swelling and inhibition of HIF1α translocation in an animal model COVID-19

Recovered COVID-19 patients often display cardiac dysfunction, even after a mild infection. Most current histological results come from patients that are hospitalized and therefore represent more severe outcomes than most COVID-19 patients face. To overcome this limitation, we investigated the cardi...

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Bibliographic Details
Main Authors: Margo Daems, Laurens Liesenborghs, Robbert Boudewijns, Steven J. Simmonds, Sirima Kraisin, Jore Van Wauwe, Ilona Cuijpers, Jana Raman, Nadèche Geuens, Tina Van Buyten, Marleen Lox, Peter Verhamme, Sophie Van Linthout, Kimberly Martinod, Stephane Heymans, Carsten Tschöpe, Johan Neyts, Elizabeth A. V. Jones
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
COVID-19
HIF1α
cardiac oedema
diastolic dysfunction
hypoxia
pericyte loss
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.964512/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.964512/full

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