A novel ex vivo lung cancer model based on bioengineered rat lungs

A novel ex vivo lung cancer model based on bioengineered rat lungs

Introduction: Two-dimensional cell cultures have contributed substantially to lung cancer research, but 3D cultures are gaining attention as a new, more efficient, and effective research model. A model reproducing the 3D characteristics and tumor microenvironment of the lungs in vivo, including the...

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Bibliographic Details
Main Authors: Satoshi Mizoguchi, Tomoshi Tsuchiya, Ryoichiro Doi, Tomohiro Obata, Mayumi Iwatake, Shintaro Hashimoto, Hirotaka Matsumoto, Hiroshi Yukawa, Hiroko Hayashi, Tao-Sheng Li, Kazuko Yamamoto, Keitaro Matsumoto, Takuro Miyazaki, Koichi Tomoshige, Takeshi Nagayasu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
decellularization
recellularization
3D culture
cancer model
bioengineering
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1179830/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1179830/full

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