Gene Expression Monotonicity across Bladder Cancer Stages Informs on the Molecular Pathogenesis and Identifies a Prognostic Eight-Gene Signature

Gene Expression Monotonicity across Bladder Cancer Stages Informs on the Molecular Pathogenesis and Identifies a Prognostic Eight-Gene Signature

Despite advancements in molecular classification, tumor stage and grade still remain the most relevant prognosticators used by clinicians to decide on patient management. Here, we leverage publicly available data to characterize bladder cancer (BLCA)’s stage biology based on increased sample sizes,...

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Bibliographic Details
Main Authors: Rafael Stroggilos, Maria Frantzi, Jerome Zoidakis, Marika Mokou, Napoleon Moulavasilis, Emmanouil Mavrogeorgis, Anna Melidi, Manousos Makridakis, Konstantinos Stravodimos, Maria G. Roubelakis, Harald Mischak, Antonia Vlahou
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
bladder cancer stage
transcriptomics
meta-analysis
molecular alterations
prognostic signature
urothelial carcinoma
Online Access:https://www.mdpi.com/2072-6694/14/10/2542

Internet

https://www.mdpi.com/2072-6694/14/10/2542

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