Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.

Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.

A dominance of Gag-specific CD8+ T cell responses is significantly associated with a lower viral load in individuals with chronic, untreated clade C human immunodeficiency virus type 1 (HIV-1) infection. This association has not been investigated in terms of Gag-specific CD4+ T cell responses, nor h...

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Bibliographic Details
Main Authors: Danni Ramduth, Cheryl L Day, Christina F Thobakgale, Nompumelelo P Mkhwanazi, Chantal de Pierres, Sharon Reddy, Mary van der Stok, Zenele Mncube, Kriebashne Nair, Eshia S Moodley, Daniel E Kaufmann, Hendrik Streeck, Hoosen M Coovadia, Photini Kiepiela, Philip J R Goulder, Bruce D Walker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2661367?pdf=render

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http://europepmc.org/articles/PMC2661367?pdf=render

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