Identification of immune-related key genes in the peripheral blood of ischaemic stroke patients using a weighted gene coexpression network analysis and machine learning

Identification of immune-related key genes in the peripheral blood of ischaemic stroke patients using a weighted gene coexpression network analysis and machine learning

Abstract Background The immune system plays a vital role in the pathological process of ischaemic stroke. However, the exact immune-related mechanism remains unclear. The current research aimed to identify immune-related key genes associated with ischaemic stroke. Methods CIBERSORT was utilized to r...

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Bibliographic Details
Main Authors: Peng-Fei Zheng, Lu-Zhu Chen, Peng Liu, Hong Wei Pan, Wen-Juan Fan, Zheng-Yu Liu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Translational Medicine
Subjects:
Weighted gene coexpression network analysis
Ischaemic stroke
Immune cell subtype distribution pattern
Significant modules
Hub genes
Online Access:https://doi.org/10.1186/s12967-022-03562-w

Internet

https://doi.org/10.1186/s12967-022-03562-w

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