<i>Epimedium</i> Aqueous Extract Ameliorates Cerebral Ischemia/Reperfusion Injury through Inhibiting ROS/NLRP3-Mediated Pyroptosis

<i>Epimedium</i> Aqueous Extract Ameliorates Cerebral Ischemia/Reperfusion Injury through Inhibiting ROS/NLRP3-Mediated Pyroptosis

Cerebral ischemia/reperfusion causes exacerbated neuronal damage involving excessive neuroinflammation and oxidative stress. ROS is considered a signal molecule to activate NLRP3; thus, the ROS/NLRP3/pyroptosis axis plays a vital role in the pathogenesis of cerebral ischemia/reperfusion injury (CIRI...

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Bibliographic Details
Main Authors: Xiaoyu Wu, Jiajia Wei, Yang Yi, Guotao Shu, Zhixu He, Qihai Gong, Jianmei Gao
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antioxidants
Subjects:
<i>Epimedium</i>
cerebral ischemic/reperfusion injury
neuron loss
neuroinflammation
NLRP3
Online Access:https://www.mdpi.com/2076-3921/12/5/999

Internet

https://www.mdpi.com/2076-3921/12/5/999

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