mRNA‐based chimeric antigen receptor T cell therapy: Basic principles, recent advances and future directions

Abstract Non‐viral vector chimeric antigen receptor (CAR)‐T cells have garnered increasing attention due to their ability to efficiently eradicate cancer cells while mitigating undesirable side effects. However, the current methods for engineering chimeric antigen receptor T (CAR‐T) cells employ vir...

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Bibliographic Details
Main Authors: Kaiting Xiao, Yanming Lai, Wenxu Yuan, Shengjie Li, Xingxing Liu, Zebin Xiao, Heng Xiao
Format: Article
Language:English
Published: Wiley-VCH 2024-01-01
Series:Interdisciplinary Medicine
Subjects:
Online Access:https://doi.org/10.1002/INMD.20230036