Stereological Analysis of Early Gene Expression Using Egr-1 Immunolabeling After Spreading Depression in the Rat Somatosensory Cortex

Stereological Analysis of Early Gene Expression Using Egr-1 Immunolabeling After Spreading Depression in the Rat Somatosensory Cortex

Early growth response-1 (Egr-1), defined as a zinc finger transcription factor, is an upstream master switch of the inflammatory response, and its expression can be used to investigate the spatial and temporal extent of inflammatory changes in the brain. Cortical spreading depression (CSD) is charac...

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Bibliographic Details
Main Authors: Marcia Consentino Kronka Sosthenes, Daniel Guerreiro Diniz, Jay Roodselaar, Ricardo Abadie-Guedes, Fabíola de Carvalho Chaves de Siqueira Mendes, Taiany Nogueira Fernandes, Jackson Cioni Bittencourt, Cristovam Wanderley Picanço Diniz, Daniel Clive Anthony, Rubem Carlos Araújo Guedes
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
Subjects:
cortical spreading depression
somatosensorial cortex
Egr-1
optical fractionator
contralateral hemisphere
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01020/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01020/full

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