Identification of a Putative Enhancer RNA for EGFR in Hyper-Accessible Regions in Esophageal Squamous Cell Carcinoma Cells by Analysis of Chromatin Accessibility Landscapes

Identification of a Putative Enhancer RNA for EGFR in Hyper-Accessible Regions in Esophageal Squamous Cell Carcinoma Cells by Analysis of Chromatin Accessibility Landscapes

Abnormal genetic and epigenetic modifications play a key role in esophageal cancer. By Assay for Transposase-Accessible Chromatin by sequencing (ATAC-seq), this study compared chromatin accessibility landscapes among two esophageal squamous cell carcinoma (ESCC) cell lines, KYSE-30 and KYSE-150, and...

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Bibliographic Details
Main Authors: Sangyong Choi, Adwait Sathe, Ewy Mathé, Chao Xing, Zui Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
esophageal cancer
ATAC-seq
AP-1
digital droplet PCR
tyrosine kinase inhibitor (TKI)
non-coding RNA (ncRNA)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.724687/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.724687/full

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