Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production.

Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production.

Toll-like receptor (TLR) 2, a type I membrane receptor that plays a key role in innate immunity, recognizes conserved molecules in pathogens, and triggering an inflammatory response. It has been associated with inflammatory and autoimmune diseases. Soluble TLR2 (sTLR2) variants have been identified...

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Bibliographic Details
Main Authors: Patricia Langjahr, David Díaz-Jiménez, Marjorie De la Fuente, Estefhany Rubio, Douglas Golenbock, Francisca C Bronfman, Rodrigo Quera, María-Julieta González, Marcela A Hermoso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0104624&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0104624&type=printable

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