Long range inter-chromosomal interaction of Oct4 distal enhancer loci regulates ESCs pluripotency
Abstract Nuclear architecture underlies the transcriptional programs within the cell to establish cell identity. As previously demonstrated, long-range chromatin interactions of the Oct4 distal enhancer (DE) are correlated with active transcription in naïve state embryonic stem cells. Here, we ident...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-02-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01363-8 |