Age-related GABAergic differences in the primary sensorimotor cortex: A multimodal approach combining PET, MRS and TMS

Healthy aging is associated with mechanistic changes in gamma-aminobutyric acid (GABA), the most abundant inhibitory neurotransmitter in the human brain. While previous work mainly focused on magnetic resonance spectroscopy (MRS)-based GABA+ levels and transcranial magnetic stimulation (TMS)-based G...

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Bibliographic Details
Main Authors: Koen Cuypers, Melina Hehl, June van Aalst, Sima Chalavi, Mark Mikkelsen, Koen Van Laere, Patrick Dupont, Dante Mantini, Stephan P. Swinnen
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:NeuroImage
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811920310211