Chorioamnionitis disrupts erythropoietin and melatonin homeostasis through the placental-fetal-brain axis during critical developmental periods

Chorioamnionitis disrupts erythropoietin and melatonin homeostasis through the placental-fetal-brain axis during critical developmental periods

Introduction: Novel therapeutics are emerging to mitigate damage from perinatal brain injury (PBI). Few newborns with PBI suffer from a singular etiology. Most experience cumulative insults from prenatal inflammation, genetic and epigenetic vulnerability, toxins (opioids, other drug exposures, envir...

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Bibliographic Details
Main Authors: Yuma Kitase, Nethra K. Madurai, Sarah Hamimi, Ryan L. Hellinger, O. Angel Odukoya, Sindhu Ramachandra, Sankar Muthukumar, Vikram Vasan, Riley Sevensky, Shannon E. Kirk, Alexander Gall, Timothy Heck, Maide Ozen, Benjamin C. Orsburn, Shenandoah Robinson, Lauren L. Jantzie
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Physiology
Subjects:
inflammation
perinatal brain injury
neurorepair
placenta
neural-immune
neuroimmunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1201699/full

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https://www.frontiersin.org/articles/10.3389/fphys.2023.1201699/full

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