Butyrate protects against MRSA pneumonia via regulating gut-lung microbiota and alveolar macrophage M2 polarization

Butyrate protects against MRSA pneumonia via regulating gut-lung microbiota and alveolar macrophage M2 polarization

ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) is a well-recognized cause of bacterial pneumonia in general. The gut microbiota and their metabolic byproducts act as important modulators of the gut-lung axis. Our investigation indicates a significant reduction in the abundance of butyra...

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Bibliographic Details
Main Authors: Yan Zhao, Haoming Sun, Yiwei Chen, Qiang Niu, Yiting Dong, Mei Li, Ye Yuan, Xiaojun Yang, Qingzhu Sun
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
MRSA pneumonia
lung microbiota
gut microbiota
sodium butyrate
alveolar macrophage
M2 polarization
Online Access:https://journals.asm.org/doi/10.1128/mbio.01987-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01987-23

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