Detailed characterization of SARS-CoV-2-specific T and B cells after infection or heterologous vaccination

Detailed characterization of SARS-CoV-2-specific T and B cells after infection or heterologous vaccination

The formation of a robust long-term antigen (Ag)-specific memory, both humoral and cell-mediated, is created following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or vaccination. Here, by using polychromatic flow cytometry and complex data analyses, we deeply investigated...

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Bibliographic Details
Main Authors: Domenico Lo Tartaro, Annamaria Paolini, Marco Mattioli, Julian Swatler, Anita Neroni, Rebecca Borella, Elena Santacroce, Alessia Di Nella, Licia Gozzi, Stefano Busani, Michela Cuccorese, Tommaso Trenti, Marianna Meschiari, Giovanni Guaraldi, Massimo Girardis, Cristina Mussini, Katarzyna Piwocka, Lara Gibellini, Andrea Cossarizza, Sara De Biasi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
antigen-specific response
polyfunctionality
T cells
B cells
cytokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1123724/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1123724/full

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