Integration of a perfusion reactor and continuous precipitation in an entirely membrane‐based process for antibody capture

Abstract Continuous precipitation coupled with continuous tangential flow filtration is a cost‐effective alternative for the capture of recombinant antibodies from crude cell culture supernatant. The removal of surge tanks between unit operations, by the adoption of tubular reactors, maintains a con...

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Bibliographic Details
Main Authors: Gabriele Recanati, Magdalena Pappenreiter, Christoph Gstoettner, Patrick Scheidl, Elena Domínguez Vega, Bernhard Sissolak, Alois Jungbauer
Format: Article
Language:English
Published: Wiley-VCH 2023-10-01
Series:Engineering in Life Sciences
Subjects:
Online Access:https://doi.org/10.1002/elsc.202300219