Integration of a perfusion reactor and continuous precipitation in an entirely membrane‐based process for antibody capture
Abstract Continuous precipitation coupled with continuous tangential flow filtration is a cost‐effective alternative for the capture of recombinant antibodies from crude cell culture supernatant. The removal of surge tanks between unit operations, by the adoption of tubular reactors, maintains a con...
Main Authors: | Gabriele Recanati, Magdalena Pappenreiter, Christoph Gstoettner, Patrick Scheidl, Elena Domínguez Vega, Bernhard Sissolak, Alois Jungbauer |
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Format: | Article |
Language: | English |
Published: |
Wiley-VCH
2023-10-01
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Series: | Engineering in Life Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1002/elsc.202300219 |
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