The role of spinal cord extrasynaptic α5GABAA receptors in chronic pain

The role of spinal cord extrasynaptic α5GABAA receptors in chronic pain

Abstract Chronic pain is an incapacitating condition that affects a large population worldwide. Until now, there is no drug treatment to relieve it. The impairment of GABAergic inhibition mediated by GABAA receptors (GABAAR) is considered a relevant factor in mediating chronic pain. Even though both...

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Bibliographic Details
Main Authors: Rodolfo Delgado‐Lezama, Mariana Bravo‐Hernández, Úrzula Franco‐Enzástiga, Yarim E. De la Luz‐Cuellar, Nara S. Alvarado‐Cervantes, Guadalupe Raya‐Tafolla, Luis A. Martínez‐Zaldivar, Alberto Vargas‐Parada, Erick J. Rodríguez‐Palma, Guadalupe C. Vidal‐Cantú, Crystell G. Guzmán‐Priego, Jorge E. Torres‐López, Janet Murbartián, Ricardo Felix, Vinicio Granados‐Soto
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Physiological Reports
Subjects:
extrasynaptic GABAA receptors
GABAA and GABAB receptors
Hoffmann reflex
Pain
Online Access:https://doi.org/10.14814/phy2.14984

Internet

https://doi.org/10.14814/phy2.14984

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