Loss of CB1 receptors leads to differential age-related changes in reward-driven learning and memory

Loss of CB1 receptors leads to differential age-related changes in reward-driven learning and memory

Previous studies have shown that cannabinoid 1 (CB1) receptor signaling dissociates between reward-associated and aversive memories. The influence of CB1 receptors on the aversion-driven spatial learning in the Morris water maze test is strongly age-dependent: mice with genetic deletion of CB1 recep...

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Bibliographic Details
Main Authors: Onder eAlbayram, Andras eBilkei-Gorzo, Andreas eZimmer
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Aging
Mice
Motivation
Cannabinoid receptor
Spatial learning
emotional valence
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2012.00034/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2012.00034/full

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