Oral Bioavailability and Lymphatic Transport of Pueraria Flavone-Loaded Self-Emulsifying Drug-Delivery Systems Containing Sodium Taurocholate in Rats

Oral Bioavailability and Lymphatic Transport of Pueraria Flavone-Loaded Self-Emulsifying Drug-Delivery Systems Containing Sodium Taurocholate in Rats

We developed self-microemulsifying drug-delivery systems (SMEDDS), including bile salts, to improve the oral bioavailability of pueraria flavones (PFs). The physical properties of the SMEDDS using Cremophor RH 40, and bile salts as mixed surfactants at weight ratios of 10:0–0:10 were deter...

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Bibliographic Details
Main Authors: Jin Qiao, Danyang Ji, Shilin Sun, Guangyuan Zhang, Xin Liu, Bingxue Sun, Qingxiang Guan
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Pharmaceutics
Subjects:
SMEDDS
pueraria flavone
in vitro release
relative bioavailability
lymphatic transport
Online Access:http://www.mdpi.com/1999-4923/10/3/147

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http://www.mdpi.com/1999-4923/10/3/147

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