Interplay between the heterotrimeric G-protein subunits G<sub>αq </sub>and G<sub>αi2 </sub>sets the threshold for chemotaxis and TCR activation
<p>Abstract</p> <p>Background</p> <p>TCR and CXCR4-mediated signaling appears to be reciprocally regulated pathways. TCR activation dampens the chemotactic response towards the CXCR4 ligand CXCL12, while T cells exposed to CXCL12 are less prone to subsequent TCR-activat...
| Հիմնական հեղինակներ: | , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
BMC
2009-05-01
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| Շարք: | BMC Immunology |
| Առցանց հասանելիություն: | http://www.biomedcentral.com/1471-2172/10/27 |