Angiotensin II-Induced Cardiac Effects Are Modulated by Endocannabinoid-Mediated CB<sub>1</sub> Receptor Activation

Angiotensin II-Induced Cardiac Effects Are Modulated by Endocannabinoid-Mediated CB<sub>1</sub> Receptor Activation

Angiotensin II (Ang II) has various cardiac effects and causes vasoconstriction. Ang II activates the type-1 angiotensin receptor—G<sub>q/11</sub> signaling pathway resulting in the release of 2-arachidonoylglycerol (2-AG). We aimed to investigate whether cardiac Ang II effects are modul...

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Bibliographic Details
Main Authors: Zsuzsanna Miklós, Dina Wafa, György L. Nádasy, Zsuzsanna E. Tóth, Balázs Besztercei, Gabriella Dörnyei, Zsófia Laska, Zoltán Benyó, Tamás Ivanics, László Hunyady, Mária Szekeres
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
Angiotensin II
cardiac
endocannabinoid
CB<sub>1</sub> cannabinoid receptor
myocardial function
coronary flow
Online Access:https://www.mdpi.com/2073-4409/10/4/724

Internet

https://www.mdpi.com/2073-4409/10/4/724

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