DHA and EPA reverse cystic fibrosis-related FA abnormalities by suppressing FA desaturase expression and activity
Patients and models of cystic fibrosis (CF) exhibit consistent abnormalities of polyunsaturated fatty acid composition, including decreased linoleate (LA) and docosahexaenoate (DHA) and variably increased arachidonate (AA), related in part to increased expression and activity of fatty acid desaturas...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-02-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520407837 |