Deep immunoglobulin repertoire sequencing depicts a comprehensive atlas of spike-specific antibody lineages shared among COVID-19 convalescents

Deep immunoglobulin repertoire sequencing depicts a comprehensive atlas of spike-specific antibody lineages shared among COVID-19 convalescents

Neutralizing antibodies are a key component in protective humoral immunity against SARS-CoV-2. Currently, available technologies cannot track epitope-specific antibodies in global antibody repertoires. Thus, the comprehensive repertoire of spike-specific neutralizing antibodies elicited by SARS-CoV-...

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Bibliographic Details
Main Authors: Qihong Yan, Yudi Zhang, Ruitian Hou, Wenjing Pan, Huan Liang, Xijie Gao, Weiqi Deng, Xiaohan Huang, Linbing Qu, Congli Tang, Ping He, Banghui Liu, Qian Wang, Xinwei Zhao, Zihan Lin, Zhaoming Chen, Pingchao Li, Jian Han, Xiaoli Xiong, Jincun Zhao, Song Li, Xuefeng Niu, Ling Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
spike
antibodyomics
antibody repertoire
epitope mapping
lineage tracking
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2290841

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2023.2290841

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