Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma

Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma

Abstract Background Hypoxia, a fundamental characteristic of glioma, is considered to promote tumor malignancy by inducing process of epithelial mesenchymal transition (EMT). Ferritin Light Chain (FTL) is one of the iron metabolism regulators and is overexpressed in glioma. However, relationship bet...

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Bibliographic Details
Main Authors: Junhui Liu, Lun Gao, Na Zhan, Pengfei Xu, Ji’an Yang, Fan’en Yuan, Yang Xu, Qiang Cai, Rongxin Geng, Qianxue Chen
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Ferritin light chain
Hypoxia
Epithelial mesenchymal transition
Chemoresistance
Glioblastoma
Prognosis
Online Access:http://link.springer.com/article/10.1186/s13046-020-01641-8

Internet

http://link.springer.com/article/10.1186/s13046-020-01641-8

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