A multi-antigenic adenoviral-vectored vaccine improves BCG-induced protection of goats against pulmonary tuberculosis infection and prevents disease progression.

The "One world, one health" initiative emphasizes the need for new strategies to control human and animal tuberculosis (TB) based on their shared interface. A good example would be the development of novel universal vaccines against Mycobacterium tuberculosis complex (MTBC) infection. This...

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Bibliographic Details
Main Authors: Bernat Pérez de Val, Enric Vidal, Bernardo Villarreal-Ramos, Sarah C Gilbert, Anna Andaluz, Xavier Moll, Maite Martín, Miquel Nofrarías, Helen McShane, H Martin Vordermeier, Mariano Domingo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3836889?pdf=render