Peli1 Contributions in Microglial Activation, Neuroinflammatory Responses and Neurological Deficits Following Experimental Subarachnoid Hemorrhage

Peli1 Contributions in Microglial Activation, Neuroinflammatory Responses and Neurological Deficits Following Experimental Subarachnoid Hemorrhage

Early brain injury (EBI) following subarachnoid hemorrhage (SAH) is closely associated with neuroinflammation. Microglial activation is an early event that leads to neuroinflammation after SAH. Peli1 is an E3 ubiquitin ligase that mediates the induction of pro-inflammatory cytokines in microglia. He...

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Bibliographic Details
Main Authors: Xue-Ping Huang, Jian-Hua Peng, Jin-Wei Pang, Xiao-Cui Tian, Xin-Shen Li, Yue Wu, Yong Li, Yong Jiang, Xiao-Chuan Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Peli1
subarachnoid hemorrhage
early brain injury
microglia
neuroinflammation
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00398/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00398/full

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