Combination of β Adrenergic Receptor Block and Renin–Angiotensin System Inhibition Diminished the Angiotensin II-Induced Vasoconstriction and Increased Bradykinin-Induced Vasodilation in Hypertension

In hypertension, the combination therapy is frequently used to obtain a better therapeutic effect and reduce adverse effects. One effective combination is with inhibitors and β-blockers of renin–angiotensin system. Although the mechanisms of action of each drug are already known, the antihypertensiv...

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Bibliographic Details
Main Authors: Diego Lezama-Martínez MD, Ignacio Valencia-Hernández PhD, Jazmin Flores-Monroy PhD, Luisa Martínez-Aguilar PhD
Format: Article
Language:English
Published: SAGE Publishing 2017-11-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325817737932