Reactivation of a silenced <it>H19</it> gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation

<p>Abstract</p> <p>Background</p> <p>The active copy of the imprinted gene <it>H19</it> is turned off by inappropriate methylation in several pediatric tumors including Wilms' Tumour and embryonal rhabdomyosarcoma. <it>H19</it> controls in &...

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Bibliographic Details
Main Authors: Bestor Timothy H, Tycko Benjamin, Lynch Catherine A, Walsh Colum P
Format: Article
Language:English
Published: BMC 2002-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/1/1/2