A Gene Expression High-Throughput Screen (GE-HTS) for Coordinated Detection of Functionally Similar Effectors in Cancer

A Gene Expression High-Throughput Screen (GE-HTS) for Coordinated Detection of Functionally Similar Effectors in Cancer

Genome-wide, loss-of-function screening can be used to identify novel vulnerabilities upon which specific tumor cells depend for survival. Functional Signature Ontology (FUSION) is a gene expression-based high-throughput screening (GE-HTS) method that allows researchers to identify functionally simi...

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Bibliographic Details
Main Authors: Chaitra Rao, Dianna H. Huisman, Heidi M. Vieira, Danielle E. Frodyma, Beth K. Neilsen, Binita Chakraborty, Suzie K. Hight, Michael A. White, Kurt W. Fisher, Robert E. Lewis
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
high-throughput screens
functional signature ontology
cancer susceptibility genes
Ras-driven cancer
Online Access:https://www.mdpi.com/2072-6694/12/11/3143

Internet

https://www.mdpi.com/2072-6694/12/11/3143

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