Structure-aware annotation of leucine-rich repeat domains.

Protein domain annotation is typically done by predictive models such as HMMs trained on sequence motifs. However, sequence-based annotation methods are prone to error, particularly in calling domain boundaries and motifs within them. These methods are limited by a lack of structural information acc...

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Bibliographic Details
Main Authors: Boyan Xu, Alois Cerbu, Christopher J Tralie, Daven Lim, Ksenia Krasileva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012526