Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins
Abstract The interactions of the antibiotic proteins colicins/pyocins with immunity proteins is a seminal model system for studying protein–protein interactions and specificity. Yet, a precise and quantitative determination of which structural elements and residues determine their binding affinity a...
| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado: |
Nature Portfolio
2021-02-01
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| Series: | Scientific Reports |
| Acceso en liña: | https://doi.org/10.1038/s41598-021-83265-2 |