Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins
Abstract The interactions of the antibiotic proteins colicins/pyocins with immunity proteins is a seminal model system for studying protein–protein interactions and specificity. Yet, a precise and quantitative determination of which structural elements and residues determine their binding affinity a...
| Main Authors: | , |
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| Format: | Article |
| Sprog: | English |
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Nature Portfolio
2021-02-01
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| Serier: | Scientific Reports |
| Online adgang: | https://doi.org/10.1038/s41598-021-83265-2 |