Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

The epigenetic mechanisms promoting lineage‐specific commitment of human skeletal (mesenchymal or stromal) stem cells (hMSCs) into adipocytes or osteoblasts are still not fully understood. Herein, we performed an epigenetic library functional screen and identified several novel compounds, including...

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Bibliographic Details
Main Authors: Dalia Ali, Rimi Hamam, Musaed Alfayez, Moustapha Kassem, Abdullah Aldahmash, Nehad M. Alajez
Format: Article
Language:English
Published: Oxford University Press 2016-08-01
Series:Stem Cells Translational Medicine
Subjects:
Epigenetic
Adipocyte
Osteoblast
Mesenchymal stem cells
Histone deacetylase inhibitors
Online Access:https://doi.org/10.5966/sctm.2015-0331

Internet

https://doi.org/10.5966/sctm.2015-0331

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