Oral vaccination of piglets against Mycoplasma hyopneumoniae using silica SBA-15 as an adjuvant effectively reduced consolidation lung lesions at slaughter

Abstract Mycoplasma (M.) hyopneumoniae is the main pathogen of porcine enzootic pneumonia (PEP). Its controlling is challenging, and requires alternative strategies. This study aimed to develop an oral vaccine against M. hyopneumoniae using a nanostructured mesoporous silica (SBA-15) as an adjuvant,...

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Bibliographic Details
Main Authors: Marina L. Mechler-Dreibi, Henrique M. S. Almeida, Karina Sonalio, Mariela A. C. Martines, Fernando A. M. Petri, Beatriz B. Zambotti, Marcela M. Ferreira, Gabriel Y. Storino, Tereza S. Martins, Hélio J. Montassier, Osvaldo A. Sant’Anna, Márcia C. A. Fantini, Luís Guilherme de Oliveira
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01883-2