Sustained therapeutic effect of an anti-inflammatory peptide encapsulated in nanoparticles on ocular vascular leakage in diabetic retinopathy

Sustained therapeutic effect of an anti-inflammatory peptide encapsulated in nanoparticles on ocular vascular leakage in diabetic retinopathy

Pigment epithelium-derived factor (PEDF), an endogenous Wnt signaling inhibitor in the serine proteinase inhibitors (SERPIN) super family, is present in multiple organs, including the vitreous. Significantly low levels of PEDF in the vitreous are found to associate with pathological retinal vascular...

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Bibliographic Details
Main Authors: Qiang Qu, Kyoungmin Park, Kevin Zhou, Drew Wassel, Rafal Farjo, Tracy Criswell, Jian-xing Ma, Yuanyuan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
pigment epithelium-derived factor
anti-inflammatory
anti-vascular leakage
diabetic retinopathy
wnt signaling
PLGA
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1049678/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1049678/full

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