Sustained therapeutic effect of an anti-inflammatory peptide encapsulated in nanoparticles on ocular vascular leakage in diabetic retinopathy

Sustained therapeutic effect of an anti-inflammatory peptide encapsulated in nanoparticles on ocular vascular leakage in diabetic retinopathy

Pigment epithelium-derived factor (PEDF), an endogenous Wnt signaling inhibitor in the serine proteinase inhibitors (SERPIN) super family, is present in multiple organs, including the vitreous. Significantly low levels of PEDF in the vitreous are found to associate with pathological retinal vascular...

Full description

Bibliographic Details
Main Authors:	Qiang Qu, Kyoungmin Park, Kevin Zhou, Drew Wassel, Rafal Farjo, Tracy Criswell, Jian-xing Ma, Yuanyuan Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	pigment epithelium-derived factor anti-inflammatory anti-vascular leakage diabetic retinopathy wnt signaling PLGA
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.1049678/full

Similar Items

Advances in mechanism on pigment epithelium derived factor in diabetes retinopathy
by: ZHOU Sifeng, ZHU Jieyun, XU Haishu, NI Ying
Published: (2024-04-01)

Case Report: Solar retinopathy following exposure to reflected sunlight
by: A.S. Krivoruchko, et al.
Published: (2019-04-01)

Findings of a study of pigment epithelium-derived factor (PEDF) levels in vitreous samples from patients with proliferative diabetic retinopathy
by: A.A. Putienko, et al.
Published: (2016-06-01)

The association between plasma concentration of pigment epithelium-derived factor and diabetic retinopathy
by: Şahin Tayfun, et al.
Published: (2023-09-01)

Encapsulation of morin in lipid core/PLGA shell nanoparticles significantly enhances its anti-inflammatory activity and oral bioavailability
by: Suhair Sunoqrot, et al.
Published: (2023-06-01)

Optical coherence tomography characteristics in hydroxychloroquine retinopathy and the correlations with visual deterioration in Taiwanese
by: Shao-Kai He, et al.
Published: (2024-12-01)

Clinical and experimental study on angiopoietin-like protein 8 associated with proliferative diabetic retinopathy
by: Chang-Xia Dong, et al.
Published: (2017-12-01)

Protective effects of pigment epithelium-derived factor against X-ray-induced retinopathy
by: ZHU Ran, et al.
Published: (2022-08-01)

Protective roles of autophagy in retinal pigment epithelium under high glucose condition via regulating PINK1/Parkin pathway and BNIP3L
by: Chengchi Huang, et al.
Published: (2018-07-01)

Drug, delivery and devices for diabetic retinopathy (3Ds in DR)
by: Natarajan, Jayaganesh V., et al.
Published: (2016)

Infection of Human Retinal Pigment Epithelial Cells with Dengue Virus Strains Isolated during Outbreaks in Singapore
by: Liam M. Ashander, et al.
Published: (2022-01-01)

Lutein Encapsulated in PLGA–Phospholipid Nano-Carrier Effectively Mitigates Cytokines by Inhibiting Tumor Necrosis Factor TNF-α and Nuclear Factor NF-<i>κ</i>B in Mice Retina
by: Ranganathan Arunkumar, et al.
Published: (2023-04-01)

Evaluation of an Intravitreal Rho-Associated Kinase Inhibitor Depot Formulation in a Rat Model of Diabetic Retinopathy
by: Cecile Lebon, et al.
Published: (2021-07-01)

Retinopathy of Prematurity
by: Kadir Kırboğa, et al.
Published: (2014-12-01)

Diabetic Retinopathy and Ocular Melanoma: How Far We Are?
by: Eliana B. Souto, et al.
Published: (2020-04-01)

Phosphoinositide Lipids in Ocular Tissues
by: Ammaji Rajala, et al.
Published: (2020-06-01)

Exudative retinal detachment and retinal pigment epithelial rip due to central serous retinopathy in eye with diabetic retinopathy
by: Kumar Saurabh, et al.
Published: (2017-01-01)

External Limiting Membrane, Photoreceptor Ellipsoid Zone Disruption, and Retinal Pigment Epithelium Alterations in Diabetic Retinopathy
by: Nibha Mishra, et al.
Published: (2022-07-01)

Evaluation of the effect of melatonin treatment on telomere length of the retinal pigment epithelium in streptozotocin-induced diabetic rat model
by: Ayla Eren Ozdemir
Published: (2024-12-01)

Serous Retinal Detachment without Leakage on Fluorescein/Indocyanine Angiography in MEK Inhibitor-Associated Retinopathy
by: Chihiro Murata, et al.
Published: (2022-07-01)

Retinopathy of prematurity-An overview
by: Natasha Radhakrishnan, et al.
Published: (2017-01-01)

Ritonavir and bull’s eye maculopathy: case report [Ritonavir und „Bull’s Eye“-Retinopathie: Fallbericht]
by: Santos, Luisa, et al.
Published: (2013-01-01)

Preparation of Poly (dl-Lactide-co-Glycolide) Nanoparticles Encapsulated with Periglaucine A and Betulinic Acid for In Vitro Anti-Acanthamoeba and Cytotoxicity Activities
by: Tooba Mahboob, et al.
Published: (2018-07-01)

Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF
by: Ruiyan Fan, et al.
Published: (2023-09-01)

Update on imaging and anti-VEGF therapy for diabetic retinopathy
by: Sagnik Sen, et al.
Published: (2022-01-01)

Morphofunctional Distinction of Retinal Pigment Epithelium in Normal and Age-related Macular Degeneration. Review of the Literature
by: R. R. Fayzrakhmanov, et al.
Published: (2024-04-01)

Antioxidative Effects of Ascorbic Acid and Astaxanthin on ARPE-19 Cells in an Oxidative Stress Model
by: Sanghyeon Oh, et al.
Published: (2020-09-01)

mpact of molecular weight of polyethylene glycol on physicochemical characteristics of polymeric nanoparticles encapsulating pimozide
by: HardipSinh Barad, et al.
Published: (2023-12-01)

Diclofenac Loaded Biodegradable Nanoparticles as Antitumoral and Antiangiogenic Therapy
by: Gerard Esteruelas, et al.
Published: (2022-12-01)

Nummular retinal pigment epithelium loss in bilateral diffuse uveal melanocytic proliferation
by: Neha Goel
Published: (2025-01-01)

A systematic review of the cost-effectiveness of anti-VEGF drugs for the treatment of diabetic retinopathy
by: Robert Hodgson, et al.
Published: (2025-01-01)

Current Practices in Treating Retinopathy of Prematurity in the Philippines
by: Kristine G. Pormida, MD, DPBO, et al.
Published: (2024-12-01)

Comparison of reactivation between ranibizumab and bevacizumab in aggressive retinopathy of prematurity: A retrospective case series
by: Anil Babanrao Gangwe, et al.
Published: (2025-01-01)

VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy
by: Alessandro Arrigo, et al.
Published: (2022-12-01)

Oxaliplatin-Related Ocular Toxicity
by: Marina Mesquida, et al.
Published: (2010-11-01)

Protective effects of Scoparia dulcis L. extract on high glucose-induced injury in human retinal pigment epithelial cells
by: Heng-Dao Lin, et al.
Published: (2023-03-01)

A study on clinical profile of central serous chorio-retinopathy
by: Shrikrishna Ingle1 , Kapil Naidu2
Published: (2019-04-01)

Cellular communication network factor 1 promotes retinal leakage in diabetic retinopathy via inducing neutrophil stasis and neutrophil extracellular traps extrusion
by: Ting Li, et al.
Published: (2024-05-01)

Сiliary body epithelium after laser and ultrasound phacofragmentation. Electron transmission microscopy in experiment. Report 2
by: S.Y. Kopayev, et al.
Published: (2014-01-01)

Association of serum levels of inflammatory cytokines with retinopathy of prematurity in preterm infants
by: Xiao Chun Ling, et al.
Published: (2024-01-01)