Dopamine negatively modulates the NCA ion channels in C. elegans.

The NALCN/NCA ion channel is a cation channel related to voltage-gated sodium and calcium channels. NALCN has been reported to be a sodium leak channel with a conserved role in establishing neuronal resting membrane potential, but its precise cellular role and regulation are unclear. The Caenorhabdi...

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Bibliographic Details
Main Authors: Irini Topalidou, Kirsten Cooper, Laura Pereira, Michael Ailion
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5638609?pdf=render