Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors

Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors

The European LeukemiaNet (ELN) criteria define the adverse genetic factors of acute myeloid leukemia (AML). AML with adverse genetic factors uniformly shows resistance to standard chemotherapy and is associated with poor prognosis. Here, we focus on the biological background and real-world etiology...

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Bibliographic Details
Main Authors: Daisuke Ikeda, SungGi Chi, Satoshi Uchiyama, Hirotaka Nakamura, Yong-Mei Guo, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
ELN classification
AML
<i>FLT3</i>-ITD with wild-type <i>NPM1</i>
<i>DEK-NUP214</i> fusion
<i>KMT2A</i> rearrangement
<i>BCR-ABL1</i> fusion
Online Access:https://www.mdpi.com/1422-0067/23/11/5950

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https://www.mdpi.com/1422-0067/23/11/5950

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