Pharmacokinetic study of gallocatechin-7-gallate from Pithecellobium clypearia Benth. in rats

Pharmacokinetic study of gallocatechin-7-gallate from Pithecellobium clypearia Benth. in rats

The pharmacokinetic profile of gallocatechin-7-gallate (J10688) was studied in rats after intravenous administration. Male and female Sprague-Dawley (SD) rats received 1, 3, and 10 mg/kg (i.v.) of J10688 and plasma drug concentrations were determined by a high performance liquid chromatography-mass...

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Bibliographic Details
Main Authors: Chao Li, Xiaowei Song, Junke Song, Xiaocong Pang, Zhe Wang, Ying Zhao, Wenwen Lian, Ailin Liu, Guanhua Du
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Gallocatechin-7-gallate
LC–MS
Pharmacokinetics
Dose proportionality
Non-compartment model
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383515001422

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http://www.sciencedirect.com/science/article/pii/S2211383515001422

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