Novel aspect of neprilysin in kidney fibrosis via ACSL4‐mediated ferroptosis of tubular epithelial cells

Abstract Although inhibition of neprilysin (NEP) might be a therapeutic strategy with the potential to improve the outcome of chronic kidney disease (CKD), the versatile function of NEP with its mechanism remains obscure in kidney fibrosis. In the study, we found that NEP was abnormally increased in...

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Bibliographic Details
Main Authors: Weijing Lai, Rongshuang Huang, Bo Wang, Min Shi, Fan Guo, Lingzhi Li, Qian Ren, Sibei Tao, Ping Fu, Liang Ma
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:MedComm
Subjects:
Online Access:https://doi.org/10.1002/mco2.330